Therapeutic drug monitoring of gabapentin: the applicability in patients with neuropathic pain
نویسندگان
چکیده
Gabapentin is an antiepileptic drug prescribed for several neuropathic pain conditions. This study aimed to evaluate gabapentin (GAB) trough plasma concentration range and the applicability of therapeutic monitoring in patients with pain. Fifty-three pain, aged 20 75, received as treatment at least 7 days. was sampled before GAB administration quantified by liquid chromatography a UV detector. ranged between 0.40 11.94 µg/mL chronic No differences were observed terms concentrations responsive non-responsive patients. Our data suggest that reference ranges suggested literature epilepsy should not be used Therapeutic shown important tool assess adherence.
منابع مشابه
Gabapentin in the treatment of neuropathic pain.
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2022
ISSN: ['2175-9790', '1984-8250']
DOI: https://doi.org/10.1590/s2175-97902022e191073